Rhein Protects against Obesity and Related Metabolic Disorders through Liver...
Liver X receptors (LXRs) play important roles in regulating cholesterol homeostasis, and lipid and energy metabolism. Therefore, LXR ligands could be used for the management of metabolic disorders. We...
View ArticleRegulation of the Src Family Kinases by Csk
The non-receptor tyrosine kinase Csk serves as an indispensable negative regulator of the Src family tyrosine kinases (SFKs) by specifically phosphorylating the negative regulatory site of SFKs,...
View ArticleTRAF Family Member-Associated NF-κB Activator (TANK) Induced by RANKL...
Osteoclasts are the principle bone-resorbing cells. Precise control of balanced osteoclast activity is indispensable for bone homeostasis. Osteoclast activation mediated by RANK-TRAF6 axis has been...
View ArticleUp-regulated miR-145 Expression Inhibits Porcine Preadipocytes...
Generally, most miRNAs that were up-regulated during differentiation promoted adipogenesis, but our research indicated that up-regulation of miR-145 in porcine preadipocytes did not promote but...
View ArticleImmunotherapies: The Blockade of Inhibitory Signals
T lymphocytes require signaling by the T cell receptor and by nonclonotypic cosignaling receptors. The costimulatory and inhibitory signals profoundly influence the course of immune responses by...
View ArticleInfluence of Carbon Monoxide on Growth and Apoptosis of Human Umbilical...
Carbon monoxide (CO) is a vasoactive molecule that is generated by vascular cells as a byproduct of heme catabolism and it plays an important physiological role in circulation system. In order to...
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